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CSF1R 抗体 (FineTest®700)

This anti-CSF1R antibody is a 大鼠 单克隆 antibody detecting CSF1R in FACS. Suitable for 小鼠.
产品编号 ABIN7675085
发货至: 中国

Quick Overview for CSF1R 抗体 (FineTest®700) (ABIN7675085)

抗原

See all CSF1R 抗体
CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CSF1R antibody is conjugated to FineTest®700

应用范围

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Flow Cytometry (FACS)

克隆位点

AFS98
  • 原理

    FineTest®700 Anti-Mouse CD115/CSF-1R Antibody

    亚型

    IgG2a, kappa
  • 应用备注

    Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    4 °C

    储存方法

    2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

    别名

    CD115

    背景

    Synonyms: CD115|CSF-1 receptor (EC:2.7.10.1)|CSF-1-R|CSF-1R|Csf1r|Csfmr|Fms|M-CSF-R|Macrophage colony-stimulating factor 1 receptor|Proto-oncogene c-Fms

    Background: CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.

    分子量

    0

    基因ID

    12978

    UniProt

    P09581

    途径

    RTK signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
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